Skeletal location of radiation-induced and naturally occurring osteosarcomas in man and dog.

In the past few years, various investigators have collected information on naturally occurring and radiation-induced bone tumors. This paper compares (a) the type and distribution of naturally occurring bone tumors in man and dog, (b) the type and distribution of bone tumors induced in man and dog by bone-seeking radionuclides, and (c) the skeletal distribution of osteosarcomas. We have compiled data from 6 major studies of bone tumors in man and dog (3, 4, 7, 13, 16, 17). The classification of these tumors into histologically distinctive types is shown in Table 1, and the skeletal distribution of the osteosarcomas is given in Table 2. Details of the 6 major studies used in assembling this comparative report are outlined in "Materials and Methods."